---
title: "TRETHERA CORP — Capability Statement"
uei: "QB66ZMAUF5P7"
cage: "7NJ74"
canonical: "https://teamingindex.com/contractor/QB66ZMAUF5P7/capability.md"
html_url: "https://teamingindex.com/contractor/QB66ZMAUF5P7"
updated: "2026-11-09T17:28:18.052Z"
generator: "TeamingIndex capability twin 1.0"
legal_name: "TRETHERA CORP"
primary_naics: "541714"
sam_status: "active"
active_exclusion: false
claimed: false
tier: "unclaimed"
---

# TRETHERA CORP

> TRETHERA CORP is a SAM.gov-registered entity based in SHERMAN OAKS, CA 91423-4807. UEI QB66ZMAUF5P7; CAGE 7NJ74; primary NAICS 541714. Compliance posture not provided. Active SAM registration.

> **Unclaimed profile:** seeded from SAM.gov and USAspending public records. The entity has not claimed it, so capabilities and compliance posture have not been provided.

## Identifiers

- **Legal business name:** TRETHERA CORP
- **UEI (SAM.gov Unique Entity ID):** QB66ZMAUF5P7
- **CAGE code:** 7NJ74
- **Entity structure:** Corporate Entity (Not Tax Exempt)
- **State of incorporation:** DE
- **Website:** <https://trethera.com/>
- **TeamingIndex profile:** <https://teamingindex.com/contractor/QB66ZMAUF5P7>
- **Profile status:** Unclaimed · seeded from SAM.gov and USAspending public records

## Location

- **Physical address (city, state, ZIP):** SHERMAN OAKS, CA 91423-4807
- **Country:** United States
- **Congressional district:** CA-32

## NAICS & PSC

| NAICS | Title | Primary | Small under SBA size standard (SAM.gov) |
| --- | --- | --- | --- |
| 541714 | Research and Development in Biotechnology (except Nanobiotechnology) | Yes | Yes |

| PSC | Name |
| --- | --- |
| 6505 | DRUGS AND BIOLOGICALS |

- **PSC names:** Acquisition.gov PSC Manual (April 2025 edition)

Size status is NAICS-specific and reflects the entity’s SAM.gov representations; check it against the size standard of the solicitation’s NAICS code.

## Socio-economic status

- Small Business (SB)

Source: SAM.gov entity registration, synced 2026-11-09. Confirm current SBA certification (8(a), HUBZone, WOSB/EDWOSB, VetCert SDVOSB/VOSB) before relying on a status for a set-aside.

## SAM registration & exclusion screening

- **Registration:** Active SAM registration
- **Registration expires:** 2027-04-16
- **Registration activated:** 2026-04-20
- **Exclusion screening (FAR subpart 9.4):** No active exclusion recorded in SAM.gov
- **Teaming eligibility:** Eligible to be proposed as a team member (active registration, no exclusion)
- **Source:** SAM.gov Entity Management, synced 2026-11-09

## Compliance posture

Compliance posture not provided by the contractor.

- Facility clearance: visible to paid members
  - Clearance levels are shown only to paying members; TeamingIndex does not advertise clearances (NISPOM 32 CFR 117.9).

## Contract vehicles

No contract vehicle holdings on file.

## Past performance

- **Total obligated, trailing 36 months (USAspending.gov):** $0
- **Award history:** 0 awards on record

No federal prime awards on record (USAspending.gov).

## Proven teaming graph

- No first-tier sub-award reports name this company yet
- Source: USAspending.gov sub-award reports (FSRS), sync date not recorded. Prime contractors report first-tier subcontracts of $30,000 or more. Amounts are reported sub-award values.

## SBIR/STTR portfolio

- SBIR/STTR awardee — Phase III-eligible for work derived from its SBIR/STTR projects
- 11 SBIR/STTR awards totaling $10.8M: SBIR Phase II 4, STTR Phase I 4, STTR Phase II 2, SBIR Phase I 1
- By agency: Department of Health and Human Services 11
- Active projects (contract end date ahead): 3
- Phase II awards ending within 12 months: 2
- SBIR Phase I, Department of Health and Human Services (National Institutes of Health), 2025, Sep 8, 2025 to Aug 31, 2026: Development of a novel, targeted small molecule inhibitor of the nucleoside salvage pathway through murine studies to enable further clinical advancement in non-small-cell lung cancer ($406,500)
- STTR Phase II, Department of Health and Human Services (National Institutes of Health), 2025, Sep 3, 2025 to Aug 31, 2027: Development of a Novel, Targeted Small Molecule Inhibitor of the Nucleoside Salvage Pathway to Treat Crohn's disease ($905,290)
- SBIR Phase II, Department of Health and Human Services (National Institutes of Health), 2025, Aug 18, 2025 to Jul 31, 2027: Development of a novel, targeted small molecule inhibitor of the nucleoside salvage pathway through combinatorial murine studies to enable further clinical advancement in prostate tumors ($1,150,000)
- SBIR Phase II, Department of Health and Human Services (National Institutes of Health), 2025, Aug 7, 2025 to Jul 31, 2028: Development of a Novel, Targeted Small Molecule Inhibitor of the Nucleoside Salvage Pathway to Treat Systemic Lupus Erythematosus ($994,978)
- SBIR Phase II, Department of Health and Human Services (National Institutes of Health), 2024, Jul 2, 2024 to Jun 30, 2026: Development of a novel, targeted small molecule inhibitor of the nucleoside salvage pathway through IND enabling studies and translational mouse models for acute disseminated encephalomyelitis (ADEM) ($2,050,000)
- STTR Phase II, Department of Health and Human Services (National Institutes of Health), 2024, Feb 1, 2024 to Jan 31, 2026: Development of a Novel, Targeted Small Molecule Inhibitor of the Nucleoside Salvage Pathway to Treat Optic Neuritis ($1,238,306)
- STTR Phase I, Department of Health and Human Services (National Institutes of Health), 2023, Sep 18, 2023 to Aug 31, 2024: Development of a Novel, Targeted Small Molecule Inhibitor of the Nucleoside Salvage Pathway to Treat Crohn's disease ($395,119)
- STTR Phase I, Department of Health and Human Services (National Institutes of Health), 2023, Aug 1, 2023 to Jul 31, 2025: Development of a Novel, Targeted Small Molecule Inhibitor of the Nucleoside Salvage Pathway to Treat Acute Disseminated Encephalomyelitis (ADEM) ($601,607)
- STTR Phase I, Department of Health and Human Services (National Institutes of Health), 2023, Jun 21, 2023 to May 31, 2025: Development of a Novel, Targeted Small Molecule Inhibitor of the Nucleoside Salvage Pathway to Treat Systemic Lupus Erythematosus ($610,850)
- SBIR Phase II, Department of Health and Human Services (National Institutes of Health), 2023, Jun 1, 2023 to May 31, 2025: Development of a Novel, Targeted Small Molecule Inhibitor of the Nucleotide Salvage Pathway to Treat Underserved Tumor Types ($2,046,375)
- Phase III: Agencies may award follow-on Phase III work without a new competition when it builds on this company’s earlier SBIR/STTR projects. Other work is competed as usual.
- Source: SBIR.gov award data file, as of Nov 12, 2026 (file published Nov 1, 2026)

## FedRAMP offerings

- No FedRAMP Marketplace listing is linked to this company
- Source: FedRAMP Marketplace, sync date not recorded

## Exclusions & screening

- Not yet checked against SAM.gov exclusions (search exclusions on SAM.gov: https://sam.gov/search/?index=ex)
- Source: SAM.gov Exclusions, sync date not recorded
- No confirmed match on the Consolidated Screening List (screened Nov 13, 2026)

## Contract vehicles on federal record

- No contract-vehicle seats on federal record are linked to this company

## GSA CALC+ rates

- No GSA CALC+ awarded ceiling rates on record for this company
- Source: GSA CALC+ awarded ceiling rates, sync date not recorded. Ceiling rates are the most an agency can be charged, not prices paid

## Capabilities & differentiators

No capability narrative published.

## Technical tags

No technical tags published.

## Teaming preferences

- Teaming preferences not published
- **Teaming requests and NDAs:** request an introduction on the TeamingIndex profile (sign-in required): <https://teamingindex.com/contractor/QB66ZMAUF5P7>

## Business development contact

No business-development contact published.

## Corporate hierarchy

- No parent entity reported in SAM.gov
- Affiliation with a parent or sister concerns can affect small-business size status (13 CFR 121.103).

## Provenance & disclaimer

- **SAM.gov entity registration** (identifiers, NAICS/PSC, size and socio-economic status, hierarchy, registration and exclusion status): synced 2026-11-09
- **USAspending.gov** (prime award history and trailing 36-month obligations): nightly sync
- **Contractor-provided profile** (capabilities, teaming preferences, self-attested compliance): not provided
- **TeamingIndex verification** (credentials marked “Verified by TeamingIndex”): no verified credentials on record; methodology: <https://teamingindex.com/verification>
- **Blind SPRS:** exact NIST SP 800-171 SPRS scores are published only when the contractor opts in; brackets are cumulative thresholds (SPRS ≥ 0, SPRS ≥ 50, SPRS ≥ 70, SPRS ≥ 85, SPRS ≥ 95, SPRS ≥ 105, SPRS = 110 (perfect)).
- **Before award:** self-attested facts have not been independently verified. Confirm registration and exclusions in SAM.gov, CMMC status and SPRS assessment currency with the contractor (DFARS 252.204-7019, -7020 and -7021), facility clearances through DCSA’s NISS, AS9100-series certificates in the IAQG OASIS database, and FedRAMP authorizations on the FedRAMP Marketplace.
- **Zero CUI:** this document contains no Controlled Unclassified Information. TeamingIndex stores verification metadata only, never SSPs, POA&Ms or DD Form 254s.
- **Machine-readable:** schema.org JSON-LD is embedded in <https://teamingindex.com/contractor/QB66ZMAUF5P7>; this twin: <https://teamingindex.com/contractor/QB66ZMAUF5P7/capability.md>; site index: <https://teamingindex.com/llms.txt>

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